Mutations in AKAP5 Disrupt Dendritic Signaling Complexes and Lead to Electrophysiological and Behavioral Phenotypes in Mice

AKAP5 (also referred to as AKAP150 in rodents and AKAP79 in humans) is a scaffolding protein that is highly expressed in neurons and targets a variety of signaling molecules to dendritic membranes. AKAP5 interacts with PKA holoenzymes containing RIIα or RIIβ as well as calcineurin (PP2B), PKC, calmo...

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Detalles Bibliográficos
Autores principales: Weisenhaus, Michael, Allen, Margaret L., Yang, Linghai, Lu, Yuan, Nichols, C. Blake, Su, Thomas, Hell, Johannes W., McKnight, G. Stanley
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859064/
https://www.ncbi.nlm.nih.gov/pubmed/20428246
http://dx.doi.org/10.1371/journal.pone.0010325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859064/
https://www.ncbi.nlm.nih.gov/pubmed/20428246
http://dx.doi.org/10.1371/journal.pone.0010325

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