Acetylation of WRN Protein Regulates Its Stability by Inhibiting Ubiquitination

BACKGROUND: WRN is a multi-functional protein involving DNA replication, recombination and repair. WRN acetylation has been demonstrated playing an important role in response to DNA damage. We previously found that WRN acetylation can regulate its enzymatic activities and nuclear distribution. METHO...

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Detalles Bibliográficos
Autores principales: Li, Kai, Wang, Rui, Lozada, Enerlyn, Fan, Wei, Orren, David K., Luo, Jianyuan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859066/
https://www.ncbi.nlm.nih.gov/pubmed/20428248
http://dx.doi.org/10.1371/journal.pone.0010341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859066/
https://www.ncbi.nlm.nih.gov/pubmed/20428248
http://dx.doi.org/10.1371/journal.pone.0010341

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