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Acetylation of WRN Protein Regulates Its Stability by Inhibiting Ubiquitination
BACKGROUND: WRN is a multi-functional protein involving DNA replication, recombination and repair. WRN acetylation has been demonstrated playing an important role in response to DNA damage. We previously found that WRN acetylation can regulate its enzymatic activities and nuclear distribution. METHO...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859066/ https://www.ncbi.nlm.nih.gov/pubmed/20428248 http://dx.doi.org/10.1371/journal.pone.0010341 |