A genetically-encoded reporter of synaptic activity in vivo

To image synaptic activity within neural circuits, we have tethered the genetically-encoded calcium indicator (GECI) GCaMP2 to synaptic vesicles by fusion to synaptophysin. The resulting reporter, SyGCaMP2, detects the electrical activity of neurons with two advantages over existing cytoplasmic GECI...

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Detalles Bibliográficos
Autores principales: Dreosti, Elena, Odermatt, Benjamin, Dorostkar, Mario M., Lagnado, Leon
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859341/
https://www.ncbi.nlm.nih.gov/pubmed/19898484
http://dx.doi.org/10.1038/nmeth.1399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859341/
https://www.ncbi.nlm.nih.gov/pubmed/19898484
http://dx.doi.org/10.1038/nmeth.1399

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