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A genetically-encoded reporter of synaptic activity in vivo

To image synaptic activity within neural circuits, we have tethered the genetically-encoded calcium indicator (GECI) GCaMP2 to synaptic vesicles by fusion to synaptophysin. The resulting reporter, SyGCaMP2, detects the electrical activity of neurons with two advantages over existing cytoplasmic GECI...

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Detalles Bibliográficos
Autores principales:	Dreosti, Elena, Odermatt, Benjamin, Dorostkar, Mario M., Lagnado, Leon
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859341/ https://www.ncbi.nlm.nih.gov/pubmed/19898484 http://dx.doi.org/10.1038/nmeth.1399

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