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Overexpression of c-erbB2 is a negative prognostic factor in anaplastic astrocytomas

The epidermal growth factor receptor (EGFR) family, consisting of four tyrosine kinase receptors, c-erbB1-4, seems to be influential in gliomagenesis. The aim of this study was to investigate EGFR gene amplification and expression of c-erbB1-4 receptor proteins in human anaplastic astrocytomas. Form...

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Detalles Bibliográficos
Autores principales: Gulati, Sasha, Ytterhus, Borgny, Granli, Unn S, Gulati, Michel, Lydersen, Stian, Torp, Sverre H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859381/
https://www.ncbi.nlm.nih.gov/pubmed/20331873
http://dx.doi.org/10.1186/1746-1596-5-18