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A novel soft-tissue in vitro model for bisphosphonate-associated osteonecrosis

BACKGROUND: Bisphosphonate (BP)-associated osteonecrosis of the jaw (ONJ) has been reported in patients receiving intravenous BP, particularly zoledronic acid (ZA). The purpose of this study was to develop an in vitro model representative of the effects BP has on soft tissue secondary to its release...

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Detalles Bibliográficos
Autores principales: Scheper, MA, Chaisuparat, R, Cullen, KJ, Meiller, TF
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859744/
https://www.ncbi.nlm.nih.gov/pubmed/20359336
http://dx.doi.org/10.1186/1755-1536-3-6