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Stochastic Modeling of B Lymphocyte Terminal Differentiation and Its Suppression by Dioxin

BACKGROUND: Upon antigen encounter, naïve B lymphocytes differentiate into antibody-secreting plasma cells. This humoral immune response is suppressed by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other dioxin-like compounds, which belong to the family of aryl hydro...

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Detalles Bibliográficos
Autores principales: Zhang, Qiang, Bhattacharya, Sudin, Kline, Douglas E, Crawford, Robert B, Conolly, Rory B, Thomas, Russell S, Kaminski, Norbert E, Andersen, Melvin E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859749/
https://www.ncbi.nlm.nih.gov/pubmed/20359356
http://dx.doi.org/10.1186/1752-0509-4-40