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Developing bones are differentially affected by compromised skeletal muscle formation

Mechanical forces are essential for normal adult bone function and repair, but the impact of prenatal muscle contractions on bone development remains to be explored in depth in mammalian model systems. In this study, we analyze skeletogenesis in two ‘muscleless’ mouse mutant models in which the form...

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Detalles Bibliográficos
Autores principales: Nowlan, Niamh C., Bourdon, Céline, Dumas, Gérard, Tajbakhsh, Shahragim, Prendergast, Patrick J., Murphy, Paula
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860222/
https://www.ncbi.nlm.nih.gov/pubmed/19948261
http://dx.doi.org/10.1016/j.bone.2009.11.026