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Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1

Autocrine priming of cells by small quantities of constitutively produced type I interferon (IFN) is a well-known phenomenon. In the absence of type I IFN priming, cells display attenuated responses to other cytokines, such as anti-viral protection in response to IFNγ. This phenomenon was proposed t...

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Detalles Bibliográficos
Autores principales: Gough, Daniel J., Messina, Nicole L., Hii, Linda, Gould, Jodee A., Sabapathy, Kanaga, Robertson, Ashley P. S., Trapani, Joseph A., Levy, David E., Hertzog, Paul J., Clarke, Christopher J. P., Johnstone, Ricky W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860501/
https://www.ncbi.nlm.nih.gov/pubmed/20436908
http://dx.doi.org/10.1371/journal.pbio.1000361