Negative Regulation of Bone Formation by the Transmembrane Wnt Antagonist Kremen-2

Wnt signalling is a key pathway controlling bone formation in mice and humans. One of the regulators of this pathway is Dkk1, which antagonizes Wnt signalling through the formation of a ternary complex with the transmembrane receptors Krm1/2 and Lrp5/6, thereby blocking the induction of Wnt signalli...

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Detalles Bibliográficos
Autores principales: Schulze, Jochen, Seitz, Sebastian, Saito, Hiroaki, Schneebauer, Michael, Marshall, Robert P., Baranowsky, Anke, Busse, Bjoern, Schilling, Arndt F., Friedrich, Felix W., Albers, Joachim, Spiro, Alexander S., Zustin, Jozef, Streichert, Thomas, Ellwanger, Kristina, Niehrs, Christof, Amling, Michael, Baron, Roland, Schinke, Thorsten
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860505/
https://www.ncbi.nlm.nih.gov/pubmed/20436912
http://dx.doi.org/10.1371/journal.pone.0010309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860505/
https://www.ncbi.nlm.nih.gov/pubmed/20436912
http://dx.doi.org/10.1371/journal.pone.0010309

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