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Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras

Alanyl-peptide nucleic acid (alanyl-PNA)/DNA chimeras are oligomers envisaged to be beneficial in efficient DNA diagnostics based on an improved molecular beacon concept. A synthesis of alanyl-PNA/DNA chimera can be based on the solid phase assembly of the oligomer with mixed oligonucleotide/peptide...

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Detalles Bibliográficos
Autores principales: Roviello, G. N., Gröschel, S., Pedone, C., Diederichsen, U.
Formato: Texto
Lenguaje:English
Publicado: Springer Vienna 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860553/
https://www.ncbi.nlm.nih.gov/pubmed/19629638
http://dx.doi.org/10.1007/s00726-009-0324-x