Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue

AIMS/HYPOTHESIS: Increasing the expression of the brown adipose tissue-specific gene uncoupling protein-1 (Ucp1) is a potential target for treating obesity. We investigated the role of DNA methylation and histone modification in Ucp1 expression in adipose cell lines and ex vivo murine adipose tissue...

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Detalles Bibliográficos
Autores principales: Shore, A., Karamitri, A., Kemp, P., Speakman, J. R., Lomax, M. A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860566/
https://www.ncbi.nlm.nih.gov/pubmed/20238096
http://dx.doi.org/10.1007/s00125-010-1701-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860566/
https://www.ncbi.nlm.nih.gov/pubmed/20238096
http://dx.doi.org/10.1007/s00125-010-1701-4

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