Cargando…

Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue

AIMS/HYPOTHESIS: Increasing the expression of the brown adipose tissue-specific gene uncoupling protein-1 (Ucp1) is a potential target for treating obesity. We investigated the role of DNA methylation and histone modification in Ucp1 expression in adipose cell lines and ex vivo murine adipose tissue...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shore, A., Karamitri, A., Kemp, P., Speakman, J. R., Lomax, M. A.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860566/ https://www.ncbi.nlm.nih.gov/pubmed/20238096 http://dx.doi.org/10.1007/s00125-010-1701-4

Ejemplares similares

The expression of UCP3 directly correlates to UCP1 abundance in brown adipose tissue
por: Hilse, Karolina E., et al.
Publicado: (2016)

Cold-Induced Changes in Gene Expression in Brown Adipose Tissue, White Adipose Tissue and Liver
por: Shore, Andrew M., et al.
Publicado: (2013)

Bone marrow adipose tissue does not express UCP1 during development or adrenergic-induced remodeling
por: Craft, Clarissa S., et al.
Publicado: (2019)

Expressions of mRNA and encoded proteins of mitochondrial uncoupling protein genes (UCP1, UCP2, and UCP3) in epicardial and mediastinal adipose tissue and associations with coronary artery disease
por: Huesca-Gómez, Claudia, et al.
Publicado: (2023)

Relationships between Uncoupling Protein Genes UCP1, UCP2 and UCP3 and Irisin Levels in Residents of the Coldest Region of Siberia
por: Nikanorova, Alena A., et al.
Publicado: (2022)

Immunophenotypic expression of UCP1 in hibernoma and other adipose/non adipose soft tissue tumours
por: Malzahn, Jessica, et al.
Publicado: (2019)

UCP1 and UCP3 Expression Is Associated with Lipid and Carbohydrate Oxidation and Body Composition
por: Oliveira, Bruno A. P., et al.
Publicado: (2016)

Transplantation of Adipose-Tissue-Engineered Constructs with CRISPR-Mediated UCP1 Activation
por: Michurina, Svetlana, et al.
Publicado: (2023)

Berberine regulates UCP1 expression by reshaping the conformation of quadruplex formed by the element of the UCP1 gene promoter : Berberine, a novel regulator of UCP-1
por: Wang, Qiuhui, et al.
Publicado: (2022)

Functional characterization of the Ucp1-associated oxidative phenotype of human epicardial adipose tissue
por: Chechi, Kanta, et al.
Publicado: (2017)

Increased UCP1 expression in the perirenal adipose tissue of patients with renal cell carcinoma
por: Li, Xueqin, et al.
Publicado: (2019)

Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis
por: Johnson, Jordan M., et al.
Publicado: (2023)

Acupuncture promotes white adipose tissue browning by inducing UCP1 expression on DIO mice
por: Shen, Weixing, et al.
Publicado: (2014)

UCP-2 and UCP-3 Proteins Are Differentially Regulated in Pancreatic Beta-Cells
por: Li, Yunfeng, et al.
Publicado: (2008)

IRX3 Overexpression Enhances Ucp1 Expression In Vivo
por: Zhang, Zhiyin, et al.
Publicado: (2021)

Anion Transport or Nucleotide Binding by Ucp2 Is Indispensable for Ucp2-Mediated Efferocytosis
por: Lee, Suho, et al.
Publicado: (2015)

Correction: UCP-2 and UCP-3 Proteins Are Differentially Regulated in Pancreatic Beta-Cells
por: Li, Yunfeng, et al.
Publicado: (2022)

UCP1 Induction during Recruitment of Brown Adipocytes in White Adipose Tissue Is Dependent on Cyclooxygenase Activity
por: Madsen, Lise, et al.
Publicado: (2010)

Role of IL-6 in Exercise Training- and Cold-Induced UCP1 Expression in Subcutaneous White Adipose Tissue
por: Knudsen, Jakob G., et al.
Publicado: (2014)

Alternative Polyadenylation and Differential Regulation of Ucp1: Implications for Brown Adipose Tissue Thermogenesis Across Species
por: Lu, Wen-Hsin, et al.
Publicado: (2021)

Ctnnb1/β-catenin inactivation in UCP1-positive adipocytes augments the browning of white adipose tissue
por: Chen, Na, et al.
Publicado: (2023)

Direct detection of brown adipose tissue thermogenesis in UCP1−/− mice by hyperpolarized (129)Xe MR thermometry
por: Antonacci, Michael A., et al.
Publicado: (2019)

Differences in [(18)F]FDG uptake in BAT of UCP1 −/− and UCP1 +/+ during adrenergic stimulation of non-shivering thermogenesis
por: McHugh, Christian T., et al.
Publicado: (2020)

HuR expression in adipose tissue mediates energy expenditure and acute thermogenesis independent of UCP1 expression
por: Anthony, Sarah R., et al.
Publicado: (2020)

SUN-585 Associations Between UCP1(rs1800592),UCP2(rs6593366) and UCP3(rs1800849) with Fasting Glucose, Body Mass Index, and Energy Expenditure
por: Figueroa-Vega, Nicté, et al.
Publicado: (2020)

Proline hydroxylase 2 (PHD2) promotes brown adipose thermogenesis by enhancing the hydroxylation of UCP1
por: Li, Fan, et al.
Publicado: (2023)

UCP2 and UCP3 polymorphisms as risk factors of insulin resistance for Indonesian obese adolescents
por: Mexitalia, M, et al.
Publicado: (2013)

Erratum to: Anion Transport or Nucleotide Binding by Ucp2 Is Indispensable for Ucp2-Mediated Efferocytosis
por: Lee, Suho, et al.
Publicado: (2015)

Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue
por: Qiu, Yan, et al.
Publicado: (2018)

Obesity-resistance of UCP1-deficient mice associates with sustained FGF21 sensitivity in inguinal adipose tissue
por: Klein Hazebroek, Marlou, et al.
Publicado: (2022)

OR07-03 UCP1 Expression In Human Brown Adipose Tissue Is Inversely Associated With Cardiometabolic Risk Factors
por: Kwok, T'ng Choong, et al.
Publicado: (2023)

Mitochondrial Uncoupling Proteins (UCP1-UCP3) and Adenine Nucleotide Translocase (ANT1) Enhance the Protonophoric Action of 2,4-Dinitrophenol in Mitochondria and Planar Bilayer Membranes
por: Žuna, Kristina, et al.
Publicado: (2021)

Thermogenic protein UCP1 and UCP3 expression in non-small cell lung cancer: relation with glycolysis and anaerobic metabolism
por: Giatromanolaki, Alexandra, et al.
Publicado: (2017)

Identification of UCP1 and UCP2 as Potential Prognostic Markers in Breast Cancer: A Study Based on Immunohistochemical Analysis and Bioinformatics
por: Yu, Xin, et al.
Publicado: (2022)

Leucine Deprivation Decreases Fat Mass by Stimulation of Lipolysis in White Adipose Tissue and Upregulation of Uncoupling Protein 1 (UCP1) in Brown Adipose Tissue
por: Cheng, Ying, et al.
Publicado: (2010)

When pigs fly, UCP1 makes heat
por: Jastroch, Martin, et al.
Publicado: (2015)

Association of UCP1 and UCP2 variants with diabetic retinopathy susceptibility in type-2 diabetes mellitus patients: a meta-analysis
por: Liu, Xujia, et al.
Publicado: (2021)

NFIA determines the cis-effect of genetic variation on Ucp1 expression in murine thermogenic adipocytes
por: Hiraike, Yuta, et al.
Publicado: (2022)

PGC-1α Is Required for Exercise- and Exercise Training-Induced UCP1 Up-Regulation in Mouse White Adipose Tissue
por: Ringholm, Stine, et al.
Publicado: (2013)

Important Trends in UCP3 Investigation
por: Pohl, Elena E., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ngo3qh8221lspc3b5a99at19em