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Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca(2+)

Voltage-dependent gating mechanisms of large conductance Ca(2+) and voltage-activated (BK) channels were investigated using two-dimensional maximum likelihood analysis of single-channel open and closed intervals. To obtain sufficient data at negative as well as positive voltages, single-channel curr...

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Detalles Bibliográficos
Autores principales: Shelley, Christopher, Niu, Xiaowei, Geng, Yanyan, Magleby, Karl L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860587/
https://www.ncbi.nlm.nih.gov/pubmed/20421372
http://dx.doi.org/10.1085/jgp.200910331