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Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca(2+)
Voltage-dependent gating mechanisms of large conductance Ca(2+) and voltage-activated (BK) channels were investigated using two-dimensional maximum likelihood analysis of single-channel open and closed intervals. To obtain sufficient data at negative as well as positive voltages, single-channel curr...
Autores principales: | Shelley, Christopher, Niu, Xiaowei, Geng, Yanyan, Magleby, Karl L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860587/ https://www.ncbi.nlm.nih.gov/pubmed/20421372 http://dx.doi.org/10.1085/jgp.200910331 |
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