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Allosteric mechanism of Ca(2+) activation and H(+)-inhibited gating of the MthK K(+) channel
MthK is a Ca(2+)-gated K(+) channel whose activity is inhibited by cytoplasmic H(+). To determine possible mechanisms underlying the channel’s proton sensitivity and the relation between H(+) inhibition and Ca(2+)-dependent gating, we recorded current through MthK channels incorporated into planar l...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860591/ https://www.ncbi.nlm.nih.gov/pubmed/20421375 http://dx.doi.org/10.1085/jgp.200910387 |