Myriocin-mediated up-regulation of hepatocyte apoA-I synthesis is associated with ERK inhibition

Sphingolipids including sphingomyelin have been implicated as potential atherogenic lipids. Studies in apoE (apolipoprotein E)-null mice have revealed that the serine palmitoyltransferase inhibitor myriocin reduces plasma levels of sphingomyelin, ceramide, sphingosine-1-phosphate and glycosphingolip...

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Detalles Bibliográficos
Autores principales: Glaros, Elias N., Kim, Woojin S., Garner, Brett
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860698/
https://www.ncbi.nlm.nih.gov/pubmed/20102334
http://dx.doi.org/10.1042/CS20090452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860698/
https://www.ncbi.nlm.nih.gov/pubmed/20102334
http://dx.doi.org/10.1042/CS20090452

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