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Myriocin-mediated up-regulation of hepatocyte apoA-I synthesis is associated with ERK inhibition

Sphingolipids including sphingomyelin have been implicated as potential atherogenic lipids. Studies in apoE (apolipoprotein E)-null mice have revealed that the serine palmitoyltransferase inhibitor myriocin reduces plasma levels of sphingomyelin, ceramide, sphingosine-1-phosphate and glycosphingolip...

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Detalles Bibliográficos
Autores principales:	Glaros, Elias N., Kim, Woojin S., Garner, Brett
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860698/ https://www.ncbi.nlm.nih.gov/pubmed/20102334 http://dx.doi.org/10.1042/CS20090452

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