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Structural Allele-Specific Patterns Adopted by Epitopes in the MHC-I Cleft and Reconstruction of MHC:peptide Complexes to Cross-Reactivity Assessment

The immune system is engaged in a constant antigenic surveillance through the Major Histocompatibility Complex (MHC) class I antigen presentation pathway. This is an efficient mechanism for detection of intracellular infections, especially viral ones. In this work we describe conformational patterns...

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Detalles Bibliográficos
Autores principales: Antunes, Dinler A., Vieira, Gustavo F., Rigo, Maurício M., Cibulski, Samuel P., Sinigaglia, Marialva, Chies, José A. B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860844/
https://www.ncbi.nlm.nih.gov/pubmed/20442757
http://dx.doi.org/10.1371/journal.pone.0010353