Organelle-Specific, Rapid Induction of Molecular Activities and Membrane Tethering

Using a series of novel chemically-inducible dimerization probes, we generated a system in which proteins were rapidly targeted to individual intracellular organelles. We demonstrated that a Ras GTPase can be activated at distinct intracellular locations and that membranes from two organelles, ER an...

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Detalles Bibliográficos
Autores principales: Komatsu, Toru, Kukelyansky, Igor, McCaffery, J. Michael, Ueno, Tasuku, Varela, Lidenys C., Inoue, Takanari
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860863/
https://www.ncbi.nlm.nih.gov/pubmed/20154678
http://dx.doi.org/10.1038/nmeth.1428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860863/
https://www.ncbi.nlm.nih.gov/pubmed/20154678
http://dx.doi.org/10.1038/nmeth.1428

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