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Organelle-Specific, Rapid Induction of Molecular Activities and Membrane Tethering
Using a series of novel chemically-inducible dimerization probes, we generated a system in which proteins were rapidly targeted to individual intracellular organelles. We demonstrated that a Ras GTPase can be activated at distinct intracellular locations and that membranes from two organelles, ER an...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860863/ https://www.ncbi.nlm.nih.gov/pubmed/20154678 http://dx.doi.org/10.1038/nmeth.1428 |