c-FLIP Degradation Mediates Sensitization of Pancreatic Cancer Cells to TRAIL-Induced Apoptosis by the Histone Deacetylase Inhibitor LBH589

Great efforts have been made to develop novel and efficacious therapeutics against pancreatic cancer to improve the treatment outcomes. Tumor-necrosis factor-related apoptosis-inducing ligand (TRAIL) is such a therapeutic cytokine with selective killing effect toward malignant cells. However, some h...

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Detalles Bibliográficos
Autores principales: Kauh, John, Fan, Songqing, Xia, Mingjing, Yue, Ping, Yang, Lily, Khuri, Fadlo R., Sun, Shi-Yong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860986/
https://www.ncbi.nlm.nih.gov/pubmed/20442774
http://dx.doi.org/10.1371/journal.pone.0010376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860986/
https://www.ncbi.nlm.nih.gov/pubmed/20442774
http://dx.doi.org/10.1371/journal.pone.0010376

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