Artemisinin-Derived Dimers Have Greatly Improved Anti-Cytomegalovirus Activity Compared to Artemisinin Monomers

BACKGROUND: Artesunate, an artemisinin-derived monomer, was reported to inhibit Cytomegalovirus (CMV) replication. We aimed to compare the in-vitro anti-CMV activity of several artemisinin-derived monomers and newly synthesized artemisinin dimers. METHODS: Four artemisinin monomers and two novel art...

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Detalles Bibliográficos
Autores principales: Arav-Boger, Ravit, He, Ran, Chiou, Chuang-Jiun, Liu, Jianyong, Woodard, Lauren, Rosenthal, Andrew, Jones-Brando, Lorraine, Forman, Michael, Posner, Gary
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860993/
https://www.ncbi.nlm.nih.gov/pubmed/20442781
http://dx.doi.org/10.1371/journal.pone.0010370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860993/
https://www.ncbi.nlm.nih.gov/pubmed/20442781
http://dx.doi.org/10.1371/journal.pone.0010370

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