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Artemisinin-Derived Dimers Have Greatly Improved Anti-Cytomegalovirus Activity Compared to Artemisinin Monomers
BACKGROUND: Artesunate, an artemisinin-derived monomer, was reported to inhibit Cytomegalovirus (CMV) replication. We aimed to compare the in-vitro anti-CMV activity of several artemisinin-derived monomers and newly synthesized artemisinin dimers. METHODS: Four artemisinin monomers and two novel art...
Autores principales: | Arav-Boger, Ravit, He, Ran, Chiou, Chuang-Jiun, Liu, Jianyong, Woodard, Lauren, Rosenthal, Andrew, Jones-Brando, Lorraine, Forman, Michael, Posner, Gary |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860993/ https://www.ncbi.nlm.nih.gov/pubmed/20442781 http://dx.doi.org/10.1371/journal.pone.0010370 |
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