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Targeted In Vivo Extracellular Matrix Formation Promotes Neovascularization in a Rodent Model of Myocardial Infarction

BACKGROUND: The extracellular matrix plays an important role in tissue regeneration. We investigated whether extracellular matrix protein fragments could be targeted with antibodies to ischemically injured myocardium to promote angiogenesis and myocardial repair. METHODOLOGY/PRINCIPAL FINDINGS: Four...

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Detalles Bibliográficos
Autores principales: Mihardja, Shirley S., Gao, Dongwei, Sievers, Richard E., Fang, Qizhi, Feng, Jinjin, Wang, Jianming, Vanbrocklin, Henry F., Larrick, James W., Huang, Manley, Dae, Michael, Lee, Randall J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860995/
https://www.ncbi.nlm.nih.gov/pubmed/20442783
http://dx.doi.org/10.1371/journal.pone.0010384