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Attenuation of Reactive Gliosis Does Not Affect Infarct Volume in Neonatal Hypoxic-Ischemic Brain Injury in Mice

BACKGROUND: Astroglial cells are activated following injury and up-regulate the expression of the intermediate filament proteins glial fibrillary acidic protein (GFAP) and vimentin. Adult mice lacking the intermediate filament proteins GFAP and vimentin (GFAP(−/−)Vim(−/−)) show attenuated reactive g...

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Detalles Bibliográficos
Autores principales: Järlestedt, Katarina, Rousset, Catherine I., Faiz, Maryam, Wilhelmsson, Ulrika, Ståhlberg, Anders, Sourkova, Hana, Pekna, Marcela, Mallard, Carina, Hagberg, Henrik, Pekny, Milos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861004/
https://www.ncbi.nlm.nih.gov/pubmed/20442854
http://dx.doi.org/10.1371/journal.pone.0010397