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Quantitative assay for the detection of the V617F variant in the Janus kinase 2 (JAK2) gene using the Luminex xMAP technology

BACKGROUND: The availability of clinically valid biomarkers contribute to improve the diagnosis and clinical management of diseases. A valine-to-phenylalanine substitution at position 617 (V617F) in the Janus kinase 2 (JAK2) gene has been recently associated with key signaling abnormalities in the t...

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Detalles Bibliográficos
Autores principales: Paradis, François W, Simard, Raynald, Gaudet, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861026/
https://www.ncbi.nlm.nih.gov/pubmed/20359349
http://dx.doi.org/10.1186/1471-2350-11-54