Direct anti-metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP-2, MMP-9 and MT1-MMP in tumours

The DNA enzyme Dz13, targeted against the oncogene c-Jun, is capable of inhibiting various model tumours in mice albeit in ectopic models of neoplasia. In previous studies using orthotopic models of disease, the inhibitory effects of Dz13 on secondary growth was a direct result of growth inhibition...

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Detalles Bibliográficos
Autores principales: Tan, Mei Lin, Choong, Peter FM, Dass, Crispin R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Primary research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861053/
https://www.ncbi.nlm.nih.gov/pubmed/20334687
http://dx.doi.org/10.1186/1475-2867-10-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861053/
https://www.ncbi.nlm.nih.gov/pubmed/20334687
http://dx.doi.org/10.1186/1475-2867-10-9

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