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Protection against the allergic airway inflammation depends on the modulation of spleen dendritic cell function and induction of regulatory T cells in mice

BACKGROUND: Allergen-induced imbalance of specific T regulatory (Treg) cells and T helper 2 cells plays a decisive role in the development of immune response against allergens. OBJECTIVE: To evaluate effects and potential mechanisms of DNA vaccine containing ovalbumin (OVA) and Fc fusion on allergic...

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Detalles Bibliográficos
Autores principales: Wang, Yaoli, Bai, Chunxue, Wang, Guansong, Wang, Diane, Cheng, Xiaoming, Huang, Jian, Jiang, Dongpo, Qian, Guisheng, Wang, Xiangdong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861055/
https://www.ncbi.nlm.nih.gov/pubmed/20334668
http://dx.doi.org/10.1186/1479-0556-8-2