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Trastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics
BACKGROUND: Early studies have demonstrated comparable levels of HER2/ErbB2 expression in both breast and ovarian cancer. Trastuzumab (Herceptin), a therapeutic monoclonal antibody directed against HER2, is FDA-approved for the treatment of both early and late stage breast cancer. However, clinical...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861058/ https://www.ncbi.nlm.nih.gov/pubmed/20346177 http://dx.doi.org/10.1186/1757-2215-3-7 |