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CCR5 Signaling Suppresses Inflammation and Reduces Adverse Remodeling of the Infarcted Heart, Mediating Recruitment of Regulatory T Cells

Myocardial infarction triggers an inflammatory reaction that is involved in cardiac remodeling. Cardiac repair is dependent on regulatory mechanisms that suppress inflammation and prevent excessive matrix degradation. Chemokine induction in the infarcted heart mediates recruitment of leukocyte subse...

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Detalles Bibliográficos
Autores principales: Dobaczewski, Marcin, Xia, Ying, Bujak, Marcin, Gonzalez-Quesada, Carlos, Frangogiannis, Nikolaos G.
Formato: Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861083/
https://www.ncbi.nlm.nih.gov/pubmed/20382703
http://dx.doi.org/10.2353/ajpath.2010.090759