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WNT4/β-Catenin Pathway Maintains Female Germ Cell Survival by Inhibiting Activin βB in the Mouse Fetal Ovary

Female germ cells are essential for organogenesis of the ovary; without them, ovarian follicles do not form and functional and structural characteristics of the ovary are lost. We and others showed previously that when either Wnt4 or β-catenin was inactivated in the fetal ovary, female germ cells un...

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Detalles Bibliográficos
Autores principales: Liu, Chia-Feng, Parker, Keith, Yao, Humphrey H.-C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861588/
https://www.ncbi.nlm.nih.gov/pubmed/20454446
http://dx.doi.org/10.1371/journal.pone.0010382