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14-3-3τ Regulates Beclin 1 and Is Required for Autophagy

BACKGROUND: Beclin 1 plays an essential role in autophagy; however, the regulation of Beclin 1 expression remains largely unexplored. An earlier ChIP-on-chip study suggested Beclin 1 could be an E2F target. Previously, we also reported that 14-3-3τ regulates E2F1 stability, and is required for the e...

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Detalles Bibliográficos
Autores principales: Wang, Bing, Ling, Shiyun, Lin, Weei-Chin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861590/
https://www.ncbi.nlm.nih.gov/pubmed/20454448
http://dx.doi.org/10.1371/journal.pone.0010409