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Src-dependent TrkA Transactivation Is Required for Pituitary Adenylate Cyclase-activating Polypeptide 38-mediated Rit Activation and Neuronal Differentiation

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a potent neuropeptide that possesses both neurotrophic and neurodevelopmental effects. Recently, the Rit GTPase was found to be activated by a novel Gα/cAMP/exchange protein activated by cyclic AMP (Epac)-dependent signaling pathway and r...

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Detalles Bibliográficos
Autores principales: Shi, Geng-Xian, Jin, Ling, Andres, Douglas A.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861617/
https://www.ncbi.nlm.nih.gov/pubmed/20219970
http://dx.doi.org/10.1091/mbc.E09-12-1033