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New Vaccine Design Based on Defective Genomes That Combines Features of Attenuated and Inactivated Vaccines

BACKGROUND: New vaccine designs are needed to control diseases associated with antigenically variable RNA viruses. Foot-and-mouth disease (FMD) is a highly contagious disease of livestock that inflicts severe economic losses. Although the current whole-virus chemically inactivated vaccine has proven...

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Detalles Bibliográficos
Autores principales: Rodríguez-Calvo, Teresa, Ojosnegros, Samuel, Sanz-Ramos, Marta, García-Arriaza, Juan, Escarmís, Cristina, Domingo, Esteban, Sevilla, Noemí
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861626/
https://www.ncbi.nlm.nih.gov/pubmed/20454676
http://dx.doi.org/10.1371/journal.pone.0010414