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Labelling of live cells using fluorescent aptamers: binding reversal with DNA nucleases

A reversible cell labelling method has been developed for non-destructive and non-invasive cell labelling and purification. Our method uses high affinity single strand DNA (ssDNA) aptamers against surface exposed target molecules on cells. The aptamers are subsequently removed from the cell surface...

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Detalles Bibliográficos
Autores principales: Terazono, Hideyuki, Anzai, Yu, Soloviev, Mikhail, Yasuda, Kenji
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861636/
https://www.ncbi.nlm.nih.gov/pubmed/20388214
http://dx.doi.org/10.1186/1477-3155-8-8