Genetic polymorphisms of MDM2 and TP53 genes are associated with risk of nasopharyngeal carcinoma in a Chinese population

BACKGROUND: The tumor suppressor TP53 and its negative regulator MDM2 play crucial roles in carcinogenesis. Previous case-control studies also revealed TP53 72Arg>Pro and MDM2 309T>G polymorphisms contribute to the risk of common cancers. However, the relationship between these two functional...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Mang, Zhang, Lei, Zhu, Xinhua, Huang, Jun, Jiang, Huifen, Hu, Sunhong, Liu, Yuehui
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861659/
https://www.ncbi.nlm.nih.gov/pubmed/20398418
http://dx.doi.org/10.1186/1471-2407-10-147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861659/
https://www.ncbi.nlm.nih.gov/pubmed/20398418
http://dx.doi.org/10.1186/1471-2407-10-147

Ejemplares similares