Cellular Localization of the Herpes Simplex Virus ICP0 Protein Dictates Its Ability to Block IRF3-Mediated Innate Immune Responses

Interferon regulatory factor 3 (IRF3) is important for innate antiviral responses; accordingly, many viruses target and inactivate IRF3. The ability of the Herpes simplex virus type 1 (HSV-1) immediate early protein ICP0 to inhibit IRF3 is controversial and has not been studied solely in the context...

Descripción completa

Detalles Bibliográficos
Autores principales: Paladino, Patrick, Collins, Susan E., Mossman, Karen L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861674/
https://www.ncbi.nlm.nih.gov/pubmed/20454685
http://dx.doi.org/10.1371/journal.pone.0010428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861674/
https://www.ncbi.nlm.nih.gov/pubmed/20454685
http://dx.doi.org/10.1371/journal.pone.0010428

Ejemplares similares