Impaired Innate Immunity in Tlr4 (−/−) Mice but Preserved CD8(+) T Cell Responses against Trypanosoma cruzi in Tlr4-, Tlr2-, Tlr9- or Myd88-Deficient Mice

The murine model of T. cruzi infection has provided compelling evidence that development of host resistance against intracellular protozoans critically depends on the activation of members of the Toll-like receptor (TLR) family via the MyD88 adaptor molecule. However, the possibility that TLR/MyD88...

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Detalles Bibliográficos
Autores principales: Oliveira, Ana-Carolina, de Alencar, Bruna C., Tzelepis, Fanny, Klezewsky, Weberton, da Silva, Raquel N., Neves, Fabieni S., Cavalcanti, Gisele S., Boscardin, Silvia, Nunes, Marise P., Santiago, Marcelo F., Nóbrega, Alberto, Rodrigues, Maurício M., Bellio, Maria
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861687/
https://www.ncbi.nlm.nih.gov/pubmed/20442858
http://dx.doi.org/10.1371/journal.ppat.1000870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861687/
https://www.ncbi.nlm.nih.gov/pubmed/20442858
http://dx.doi.org/10.1371/journal.ppat.1000870

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