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Accurately Measuring Recombination between Closely Related HIV-1 Genomes
Retroviral recombination is thought to play an important role in the generation of immune escape and multiple drug resistance by shuffling pre-existing mutations in the viral population. Current estimates of HIV-1 recombination rates are derived from measurements within reporter gene sequences or ge...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861704/ https://www.ncbi.nlm.nih.gov/pubmed/20442872 http://dx.doi.org/10.1371/journal.pcbi.1000766 |