Human Telomeres Are Hypersensitive to UV-Induced DNA Damage and Refractory to Repair

Telomeric repeats preserve genome integrity by stabilizing chromosomes, a function that appears to be important for both cancer and aging. In view of this critical role in genomic integrity, the telomere's own integrity should be of paramount importance to the cell. Ultraviolet light (UV), the...

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Detalles Bibliográficos
Autores principales: Rochette, Patrick J., Brash, Douglas E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861706/
https://www.ncbi.nlm.nih.gov/pubmed/20442874
http://dx.doi.org/10.1371/journal.pgen.1000926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861706/
https://www.ncbi.nlm.nih.gov/pubmed/20442874
http://dx.doi.org/10.1371/journal.pgen.1000926

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