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Human Telomeres Are Hypersensitive to UV-Induced DNA Damage and Refractory to Repair
Telomeric repeats preserve genome integrity by stabilizing chromosomes, a function that appears to be important for both cancer and aging. In view of this critical role in genomic integrity, the telomere's own integrity should be of paramount importance to the cell. Ultraviolet light (UV), the...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861706/ https://www.ncbi.nlm.nih.gov/pubmed/20442874 http://dx.doi.org/10.1371/journal.pgen.1000926 |