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Blood Fluke Exploitation of Non-Cognate CD4(+) T Cell Help to Facilitate Parasite Development

Schistosoma blood flukes, which infect over 200 million people globally, co-opt CD4(+) T cell-dependent mechanisms to facilitate parasite development and egg excretion. The latter requires Th2 responses, while the mechanism underpinning the former has remained obscure. Using mice that are either def...

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Detalles Bibliográficos
Autores principales: Lamb, Erika W., Walls, Colleen D., Pesce, John T., Riner, Diana K., Maynard, Sean K., Crow, Emily T., Wynn, Thomas A., Schaefer, Brian C., Davies, Stephen J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861709/
https://www.ncbi.nlm.nih.gov/pubmed/20442785
http://dx.doi.org/10.1371/journal.ppat.1000892