RNA Polymerase Activity and Specific RNA Structure Are Required for Efficient HCV Replication in Cultured Cells

We have previously reported that the NS3 helicase (N3H) and NS5B-to-3′X (N5BX) regions are important for the efficient replication of hepatitis C virus (HCV) strain JFH-1 and viral production in HuH-7 cells. In the current study, we investigated the relationships between HCV genome replication, viru...

Descripción completa

Detalles Bibliográficos
Autores principales: Murayama, Asako, Weng, Leiyun, Date, Tomoko, Akazawa, Daisuke, Tian, Xiao, Suzuki, Tetsuro, Kato, Takanobu, Tanaka, Yasuhito, Mizokami, Masashi, Wakita, Takaji, Toyoda, Tetsuya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861710/
https://www.ncbi.nlm.nih.gov/pubmed/20442786
http://dx.doi.org/10.1371/journal.ppat.1000885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861710/
https://www.ncbi.nlm.nih.gov/pubmed/20442786
http://dx.doi.org/10.1371/journal.ppat.1000885

Ejemplares similares