Inhibition of Cancer Cell Proliferation and Metastasis by Insulin Receptor Downregulation

Insulin receptor (IR) and the type I IGF receptor (IGF1R) are structurally and functionally related. The function of IGF1R in cancer has been well documented and anti-IGF1R strategies to treat cancer have shown initial positive results. However, the role of IR in tumor biology, independent of IGF1R,...

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Detalles Bibliográficos
Autores principales: Zhang, Hua, Fagan, Dedra H., Zeng, Xianke, Freeman, Katie T., Sachdev, Deepali, Yee, Douglas
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861724/
https://www.ncbi.nlm.nih.gov/pubmed/20154728
http://dx.doi.org/10.1038/onc.2010.17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861724/
https://www.ncbi.nlm.nih.gov/pubmed/20154728
http://dx.doi.org/10.1038/onc.2010.17

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