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Effect of probe characteristics on the subtractive hybridization efficiency of human genomic DNA
BACKGROUND: The detection sensitivity of low abundance pathogenic species by polymerase chain reaction (PCR) can be significantly enhanced by removing host nucleic acids. This selective removal can be performed using a magnetic bead-based solid phase with covalently immobilized capture probes. One o...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862039/ https://www.ncbi.nlm.nih.gov/pubmed/20406484 http://dx.doi.org/10.1186/1756-0500-3-109 |