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Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation

BACKGROUND: Mercury is a prominent environmental contaminant that causes detrimental effects to human health. Although the liver has been known to be a main target organ, there is limited information on in vivo molecular mechanism of mercury-induced toxicity in the liver. By using transcriptome anal...

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Detalles Bibliográficos
Autores principales: Ung, Choong Yong, Lam, Siew Hong, Hlaing, Mya Myintzu, Winata, Cecilia Lanny, Korzh, Svetlana, Mathavan, Sinnakaruppan, Gong, Zhiyuan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862047/
https://www.ncbi.nlm.nih.gov/pubmed/20353558
http://dx.doi.org/10.1186/1471-2164-11-212