E3 Ligase Nedd4 Promotes Axon Branching by Downregulating PTEN

Regulated protein degradation via the ubiquitin-proteasome system (UPS) plays a central role in building synaptic connections, yet little is known about either which specific UPS components are involved or UPS targets in neurons. We report that inhibiting the UPS in developing Xenopus retinal gangli...

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Detalles Bibliográficos
Autores principales: Drinjakovic, Jovana, Jung, Hosung, Campbell, Douglas S., Strochlic, Laure, Dwivedy, Asha, Holt, Christine E.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862300/
https://www.ncbi.nlm.nih.gov/pubmed/20159448
http://dx.doi.org/10.1016/j.neuron.2010.01.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862300/
https://www.ncbi.nlm.nih.gov/pubmed/20159448
http://dx.doi.org/10.1016/j.neuron.2010.01.017

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