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E3 Ligase Nedd4 Promotes Axon Branching by Downregulating PTEN
Regulated protein degradation via the ubiquitin-proteasome system (UPS) plays a central role in building synaptic connections, yet little is known about either which specific UPS components are involved or UPS targets in neurons. We report that inhibiting the UPS in developing Xenopus retinal gangli...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862300/ https://www.ncbi.nlm.nih.gov/pubmed/20159448 http://dx.doi.org/10.1016/j.neuron.2010.01.017 |